Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229980 | 0.88 | GRIN2D (0.38) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| Water SCHEMBL343274 | 0.86 | GRIN2D (0.36) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| Fluoride SCHEMBL22204318 | 0.86 | GRIN2D (0.36) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL28180581 | 0.86 | LMNA (0.40) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| Sulfuric Acid SCHEMBL15345274 | 0.82 | GRIN2D (0.33) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL15345288 | 0.80 | THRB (0.34) | TSHR | |
| SCHEMBL28210770 | 0.71 | PKM (0.39) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| SCHEMBL9016613 | 0.71 | GRIN2D (0.35) | SLC22A2SLC22A1GRIN2DGRIN3BLMNA | |
| SCHEMBL6854205 | 0.70 | GRIN2D (0.38) | PKMSLC22A2SLC22A1GRIN2DGRIN3B | |
| Amantadine SCHEMBL1073029 | 0.68 | LMNA (0.68) | PKMSLC22A2SLC22A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657190-A1 | CHABAZITE TYPE ZEOLITE AND PROCESS FOR PRODUCTION THEREOF, COPPER-CARRYING LOW-SILICA ZEOLITE, NOX REDUCTIVE ELIMINATION CATALYST INCLUDING SAID ZEOLITE, AND METHOD FOR REDUCTIVE ELIMINATION OF NOX EMPLOYING SAID CATALYST | Tosoh Corporation (JP) | 2013-10-30 | — | — | EP | disclosed |