Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.67 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | NPY1R | P25929 | 2/20 | 0.53 |
| ▸ | NPY2R | P49146 | 2/20 | 0.53 |
| ▸ | NPY4R | P50391 | 2/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159887 | 0.92 | NAALAD2 (0.59) | FOLH1ACENAALAD2SLC7A5MME | |
| SCHEMBL159886 | 0.92 | NAALAD2 (0.59) | FOLH1ACENAALAD2SLC7A5MME | |
| SCHEMBL15345879 | 0.91 | LTA4H (0.62) | FOLH1ACELTA4HMME | |
| D-Glutamate SCHEMBL4396908 | 0.88 | NAALAD2 (0.66) | FOLH1ACENAALAD2SLC7A5MME | |
| Glutamic Acid SCHEMBL4396913 | 0.88 | NAALAD2 (0.66) | FOLH1ACENAALAD2SLC7A5MME | |
| SCHEMBL16927660 | 0.85 | FOLH1 (0.64) | FOLH1ACENAALAD2MMECPA1 | |
| SCHEMBL4388459 | 0.84 | BACE1 (0.57) | LTA4HMME | |
| SCHEMBL13585297 | 0.83 | NOD1 (0.58) | FOLH1SLC7A5 | |
| SCHEMBL9628017 | 0.83 | NOD1 (0.58) | FOLH1SLC7A5 | |
| SCHEMBL234160 | 0.83 | NOD1 (0.58) | FOLH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164977-B1 | BIOMARKERS FOR PRE-DIABETES AND METHODS USING THE SAME | METABOLON INC (US) | 2013-10-30 | — | — | EP | disclosed |