Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364118 | 1.00 | PTPRC (0.45) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL7392371 | 0.70 | MAOA (0.38) | PTPRCALDH1A1L3MBTL1MAOACYP3A4 | |
| SCHEMBL4552082 | 0.70 | MAOA (0.38) | PTPRCALDH1A1L3MBTL1MAOACYP3A4 | |
| SCHEMBL1578324 | 0.69 | PTPRC (0.67) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL28547340 | 0.69 | PTPRC (0.67) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL5493737 | 0.67 | ALDH1A1 (0.68) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL3036922 | 0.66 | CYP3A4 (0.57) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL7389021 | 0.66 | ALDH1A1 (0.67) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL2048985 | 0.65 | ALDH1A1 (0.48) | PTPRCADORA2AALDH1A1L3MBTL1FGR | |
| SCHEMBL29490146 | 0.65 | ALDH1A1 (0.48) | PTPRCADORA2AALDH1A1L3MBTL1FGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375004-B2 | 5-halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | CYP3A5, CBR3, HDHD5 | PTPRC 1185/4885ADORA2A 4655/4885ALDH1A1 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.