Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263020 | 0.88 | MAPT (0.45) | ADORA3ADORA2AADORA2BADORA1MAPT | |
| SCHEMBL31120318 | 0.81 | KDM4E (0.48) | MAPTLMNARXFP1CYP19A1NPC1 | |
| SCHEMBL31120321 | 0.79 | CYP19A1 (0.66) | ADORA3ADORA2AADORA2BADORA1MAPT | |
| SCHEMBL4259280 | 0.77 | CASP3 (0.41) | MAPTLMNARXFP1CYP19A1NPC1 | |
| SCHEMBL2658159 | 0.76 | MAPT (0.46) | ADORA2AADORA1MAPTLMNARXFP1 | |
| SCHEMBL935142 | 0.73 | LTA4H (0.57) | MAPTNPC1MAPK1L3MBTL1HPGD | |
| SCHEMBL3263453 | 0.72 | KDM4E (0.37) | ADORA3ADORA2AMAPTLMNARXFP1 | |
| Hydrogen Sulfide SCHEMBL29031294 | 0.72 | LTA4H (0.55) | MAPTNPC1MAPK1L3MBTL1HPGD | |
| SCHEMBL9686298 | 0.72 | LTA4H (0.55) | MAPTNPC1MAPK1L3MBTL1HPGD | |
| SCHEMBL15364087 | 0.71 | CASP3 (0.52) | ADORA3ADORA2AADORA2BADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104059058-A | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC | 2014-09-24 | — | — | CN | claimed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | ADORA3 2438/4885ADORA2A 4029/4885ADORA2B 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.