Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258699 | 0.86 | RAB9A (0.44) | KDM4EMAPTRXFP1LMNAALDH1A1 | |
| SCHEMBL3250263 | 0.84 | LMNA (0.37) | KDM4EMAPTRXFP1LMNAALDH1A1 | |
| SCHEMBL3263020 | 0.77 | MAPT (0.45) | KDM4EMAPTRXFP1LMNAALDH1A1 | |
| SCHEMBL13930905 | 0.76 | SMN1; SMN2 (0.56) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL4255751 | 0.75 | ALOX15 (0.43) | KDM4EMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL14488484 | 0.75 | NPC1 (0.43) | BCHERAB9ANPC1 | |
| SCHEMBL31120318 | 0.75 | KDM4E (0.48) | KDM4EMAPTRXFP1LMNAALDH1A1 | |
| SCHEMBL15364181 | 0.72 | ADORA3 (0.50) | KDM4EMAPTRXFP1LMNAALDH1A1 | |
| SCHEMBL15364221 | 0.70 | ALOX15 (0.43) | KDM4EMAPTLMNAALDH1A1BCHE | |
| SCHEMBL4259280 | 0.68 | CASP3 (0.41) | KDM4EMAPTRXFP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-10112930-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2017-12-28 | — | — | US | disclosed |
| EP-2786994-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-3233080-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | Monsanto Technology LLC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | disclosed |
| EP-2786994-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786992-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786993-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| CN-101820761-B | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC | 2013-09-04 | — | — | CN | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| CN-101820761-A | Compositions and methods for controlling nematodes | DIVERGENCE INC | 2010-09-01 | — | — | CN | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-10112930-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | KDM4E 1933/4885MAPT 2871/4885RXFP1 4046/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | CYP51A1, MT-CO3, ACOX3 | KDM4E 1960/4885MAPT 2234/4885RXFP1 4253/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | KDM4E 2135/4885MAPT 1040/4885RXFP1 3596/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | KDM4E 2052/4885MAPT 2961/4885RXFP1 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.