Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255751 | 0.90 | ALOX15 (0.43) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL15364410 | 0.87 | ALOX15 (0.54) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL15364034 | 0.85 | ALOX15 (0.43) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL3263006 | 0.85 | ALOX15 (0.43) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL3261757 | 0.79 | ALOX15 (0.54) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL3263388 | 0.79 | PIK3R1 (0.49) | ALOX15PIK3CAPIK3R1MAPTADORA3 | |
| SCHEMBL15364087 | 0.78 | CASP3 (0.52) | ALOX15PIK3CAPIK3R1CASP3MAPT | |
| SCHEMBL3250295 | 0.77 | NPC1 (0.40) | ALOX15PTGS2CASP3MAPTADORA2A | |
| SCHEMBL3262950 | 0.77 | ALOX15 (0.43) | ALOX15PTGS2PIK3CAPIK3R1CASP3 | |
| SCHEMBL13930942 | 0.75 | CASP3 (0.63) | ALOX15PTGS2PIK3CAPIK3R1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | ALOX15 589/4885PTGS2 1425/4885PIK3CA 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.