Sugi Predict

Sugi Predict / Compounds / SCHEMBL3262950

SCHEMBL3262950

SCHEMBL3262950

Cc1cc(Cl)ccc1-c1nsc(-c2ccco2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.43
▸ PTGS2 P35354 1/20 0.43
▸ PIK3CA P42336 2/20 0.42
▸ PIK3R1 P27986 1/20 0.42
▸ RARA P10276 1/20 0.40
▸ RARB P10826 1/20 0.40
▸ RARG P13631 1/20 0.40
▸ CASP3 P42574 2/20 0.40
▸ ANO1 Q5XXA6 1/20 0.39
▸ NOTUM Q6P988 1/20 0.39
▸ KMT2A Q03164 4/20 0.38
▸ MAPT P10636 4/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ ALOX12 P18054 2/20 0.38
▸ USP2 O75604 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3263006 0.90 ALOX15 (0.43) ALOX15PTGS2PIK3CAPIK3R1RARA
SCHEMBL3261757 0.87 ALOX15 (0.54) ALOX15PTGS2PIK3CAPIK3R1RARA
SCHEMBL13946477 0.86 RARA (0.36) ALOX15RARARARBRARGKMT2A
SCHEMBL4256782 0.85 PIK3R1 (0.42) ALOX15PIK3CAPIK3R1RARARARB
SCHEMBL4255751 0.85 ALOX15 (0.43) ALOX15PTGS2PIK3CAPIK3R1CASP3
SCHEMBL3263401 0.82 HPGD (0.46) KMT2AMAPTALDH1A1HSD17B10MEN1
SCHEMBL15364410 0.79 ALOX15 (0.54) ALOX15PTGS2PIK3CAPIK3R1CASP3
SCHEMBL3266862 0.79 ALDH1A1 (0.36) ALOX15PTGS2PIK3CAPIK3R1RARA
SCHEMBL3264604 0.78 CASP3 (0.56) ALOX15PIK3CAPIK3R1CASP3KMT2A
SCHEMBL3247231 0.77 PIK3R1 (0.42) ALOX15PTGS2PIK3CAPIK3R1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US claimed
EP-2786994-B1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2017-11-22 — — EP claimed
US-20170152247-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2017-06-01 — — US claimed
US-9125410-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2015-09-08 — — US claimed
EP-2786994-A1 Compositions and methods for controlling nematodes Monsanto Technology LLC (US) 2014-10-08 — — EP claimed
US-10827753-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2020-11-10 — — US disclosed
US-10827753-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2020-11-10 — — US disclosed
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-11-14 — — US disclosed
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-11-14 — — US disclosed
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US disclosed
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 — — US disclosed
US-10375958-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2019-08-13 — — US disclosed
US-8435999-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2013-05-07 — — US disclosed
US-8435999-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2013-05-07 — — US disclosed
EP-2184989-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES Divergence, Inc. (US) 2010-05-19 — — EP disclosed
WO-2009023721-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES DIVERGENCE, INC. (US) 2009-02-19 — — WO disclosed
WO-2009023721-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES DIVERGENCE, INC. (US) 2009-02-19 — — WO disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed
US-20090048311-A1 Compostions and Methods for Controlling Nematodes MONSANTO TECHNOLOGY LLC 2009-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152247-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS ALOX15 550/4885PTGS2 1250/4885PIK3CA 1361/4885
US-10827753-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS ALOX15 550/4885PTGS2 1250/4885PIK3CA 1361/4885
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS ALOX15 550/4885PTGS2 1250/4885PIK3CA 1361/4885
US-20090048311-A1 Compostions and Methods for Controlling Nematodes NOP2, MT-CO3, CLPX ALOX15 1349/4885PTGS2 1432/4885PIK3CA 1684/4885
US-10375958-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS ALOX15 550/4885PTGS2 1250/4885PIK3CA 1361/4885
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS ALOX15 550/4885PTGS2 1250/4885PIK3CA 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.