Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899988 | 0.87 | SMYD3 (0.48) | SMYD3 | |
| SCHEMBL19133764 | 0.81 | HDAC4 (0.47) | HDAC4HDAC6SMYD3SLC6A5AURKA | |
| SCHEMBL2222201 | 0.79 | CARM1 (0.51) | HDAC4HDAC6SLC6A5CARM1PRMT6 | |
| SCHEMBL30365687 | 0.77 | ALDH1A1 (0.62) | WNT1DYRK1A | |
| SCHEMBL30419263 | 0.77 | SMYD3 (0.69) | SMYD3 | |
| SCHEMBL3955552 | 0.77 | ALDH1A1 (0.62) | WNT1DYRK1A | |
| SCHEMBL23388221 | 0.76 | SLC6A5 (0.48) | HDAC4HDAC6SMYD3SLC6A5AURKA | |
| SCHEMBL15366968 | 0.76 | SMYD3 (0.67) | SMYD3 | |
| SCHEMBL1570033 | 0.74 | DYRK1A (0.49) | AURKAAURKBRIPK2WNT1DYRK1A | |
| SCHEMBL16415945 | 0.74 | ALDH1A1 (0.53) | SMYD3RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100095-B2 | Resistant mutant 90 kDa heat shock protein | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-10-16 | — | — | US | disclosed |
| US-20160311871-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-10-27 | — | — | US | disclosed |
| EP-3064582-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | Taiho Pharmaceutical Co., Ltd. (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2662357-B1 | BICYCLIC COMPOUNDS OR SALTS THEREOF FOR USE IN THE TREATMENT OF CANCER | TAIHO PHARMACEUTICAL CO LTD (JP) | 2016-08-03 | — | — | EP | disclosed |
| US-8912181-B2 | Bicyclic compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| EP-2662357-A1 | NOVEL BICYCLIC COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-20130296320-A1 | NOVEL BICYCLIC COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311871-A1 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN | HSP90AB1, HSP90AA1, HSP90AB2P | HDAC4 2243/4885HDAC6 694/4885SMYD3 2596/4885 |
| US-10100095-B2 | Resistant mutant 90 kDa heat shock protein | HSP90AB1, HSP90AA1, HSP90AB2P | HDAC4 2243/4885HDAC6 694/4885SMYD3 2596/4885 |
| US-20130296320-A1 | NOVEL BICYCLIC COMPOUND OR SALT THEREOF | HSP90AB1, HSP90AA1, HSP90AB2P | HDAC4 174/4885HDAC6 49/4885SMYD3 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.