SCHEMBL15375308

SCHEMBL15375308

CCc1ccc(CC)c(OCc2ccccc2C(O)C#N)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PDCD1 Q15116 2/20 0.34
CD274 Q9NZQ7 2/20 0.34
SGMS2 Q8NHU3 8/20 0.33
ALDH1A1 P00352 4/20 0.33
LMNA P02545 3/20 0.33
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
FFAR4 Q5NUL3 3/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
FOLH1 Q04609 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375397 0.90 FFAR4 (0.35) MAPTL3MBTL1NPSR1CD274SGMS2
SCHEMBL15375461 0.87 MAPT (0.46) MAPTL3MBTL1NPSR1SGMS2ALDH1A1
SCHEMBL15375617 0.85 POLB (0.39) MAPTL3MBTL1ALDH1A1LMNAFFAR4
SCHEMBL27940412 0.85 POLB (0.39) MAPTL3MBTL1ALDH1A1LMNAFFAR4
SCHEMBL15375581 0.82 FFAR1 (0.41) MAPTL3MBTL1FFAR4KDM4ENPC1
SCHEMBL15375420 0.81 FABP4 (0.49) PDCD1CD274FABP4FABP5FFAR4
SCHEMBL1539448 0.81 MAPT (0.39) MAPTL3MBTL1NPSR1ALDH1A1LMNA
SCHEMBL1539456 0.81 MAPT (0.39) MAPTL3MBTL1NPSR1ALDH1A1LMNA
SCHEMBL1539421 0.81 MAPT (0.39) MAPTL3MBTL1NPSR1ALDH1A1LMNA
SCHEMBL15375287 0.81 FABP4 (0.38) MAPTL3MBTL1NPSR1ALDH1A1FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA MAPT 3967/4885L3MBTL1 2775/4885NPSR1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.