Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295339 | 0.98 | TSHR (0.41) | TSHRKDM4EPKMAPOBEC3AAPOBEC3G | |
| SCHEMBL29388199 | 0.98 | TSHR (0.41) | TSHRKDM4EPKMAPOBEC3AAPOBEC3G | |
| Sulfuric Acid SCHEMBL29203158 | 0.91 | KDM4E (0.38) | TSHRKDM4EPKMAPOBEC3AAPOBEC3G | |
| Sulfuric Acid SCHEMBL29203159 | 0.89 | KDM4E (0.37) | TSHRKDM4EPKMAPOBEC3AAPOBEC3G | |
| SCHEMBL29724065 | 0.82 | TDP1 (0.45) | KDM4EPKMAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL15915666 | 0.82 | TDP1 (0.45) | KDM4EPKMAPOBEC3AAPOBEC3GLMNA | |
| SCHEMBL29388369 | 0.81 | GGPS1 (0.34) | KDM4ELMNAGGPS1 | |
| SCHEMBL193561 | 0.81 | GGPS1 (0.34) | KDM4ELMNAGGPS1 | |
| SCHEMBL21490429 | 0.81 | TSHR (0.44) | TSHRKDM4ELMNANPSR1L3MBTL1 | |
| SCHEMBL514918 | 0.81 | TP53 (0.50) | KDM4EPKMAPOBEC3AAPOBEC3GLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662332-B1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | NIPPON SODA CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| US-9233849-B2 | Process for producing fluorine-containing sulfonylimide salt | NIPPON SODA CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20130323155-A1 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE SALT | NIPPON SODA CO., LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| EP-2662332-A1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | Nippon Soda Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |