SCHEMBL15375441

SCHEMBL15375441

CCCCOC(=O)C(O)c1ccccc1COc1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
PPARG P37231 3/20 0.43
PTGES O14684 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARA Q07869 1/20 0.43
APAF1 O14727 1/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
KMT2A Q03164 1/20 0.42
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375323 0.93 TDP1 (0.46) TDP1RXRARXRBRXRGFABP4
SCHEMBL15375537 0.89 TDP1 (0.52) TDP1RXRARXRBRXRGFABP4
SCHEMBL15401631 0.89 TSHR (0.44) TDP1PPARGPPARAKMT2ATSHR
SCHEMBL15375470 0.84 RXRA (0.45) TDP1RXRARXRBRXRGPOLB
SCHEMBL15375320 0.83 RXRA (0.45) TDP1RXRARXRBRXRGKMT2A
SCHEMBL15375407 0.81 FFAR4 (0.43) TDP1RXRARXRBRXRGFABP4
SCHEMBL15402404 0.81 TSHR (0.43) TDP1PPARGPPARAUSP2KMT2A
SCHEMBL15375447 0.81 FABP4 (0.57) TDP1RXRARXRBRXRGPOLB
SCHEMBL15375309 0.81 RXRA (0.42) TDP1RXRARXRBRXRGFABP4
SCHEMBL15375521 0.80 RXRA (0.46) TDP1RXRARXRBRXRGFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA TDP1 4654/4885RXRA 1438/4885RXRB 2062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.