SCHEMBL15375320

SCHEMBL15375320

Cc1ccccc1OCc1ccccc1C(O)C(=O)OCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
KDM4E B2RXH2 2/20 0.43
CYP1A2 P05177 1/20 0.43
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.40
ALOX15 P16050 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375537 0.88 TDP1 (0.52) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375529 0.88 PTGDR2 (0.41) CYP1A2TDP1ALDH1A1TSHRKMT2A
SCHEMBL15375407 0.86 FFAR4 (0.43) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375470 0.86 RXRA (0.45) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375323 0.85 TDP1 (0.46) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375441 0.83 TDP1 (0.47) RXRARXRBRXRGKDM4EFABP4
SCHEMBL15375447 0.83 FABP4 (0.57) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375309 0.82 RXRA (0.42) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15375521 0.82 RXRA (0.46) RXRARXRBRXRGKDM4ECYP1A2
SCHEMBL15402252 0.80 ALDH1A1 (0.47) RXRARXRBRXRGKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA RXRA 1438/4885RXRB 2062/4885RXRG 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.