SCHEMBL15375447

SCHEMBL15375447

Cc1ccccc1OCc1ccccc1C(O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.57
FABP5 Q01469 2/20 0.57
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
SLC1A5 Q15758 1/20 0.47
RECQL P46063 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.45
KDM4E B2RXH2 2/20 0.44
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
NOTUM Q6P988 1/20 0.43
HTT P42858 1/20 0.43
POLB P06746 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375521 0.87 RXRA (0.46) FABP4FABP5RXRARXRBRXRG
SCHEMBL8014177 0.87 RXRA (0.51) FABP4FABP5RXRARXRBRXRG
SCHEMBL15375619 0.87 MRGPRX4 (0.50) FABP4FABP5ALDH1A1FFAR4SMN1; SMN2
SCHEMBL4241913 0.87 FABP4 (0.50) FABP4FABP5PTGDR2KDM4ECYP1A2
SCHEMBL15375527 0.86 FABP4 (0.52) FABP4FABP5SLC1A5PTGDR2FFAR4
SCHEMBL15375537 0.86 TDP1 (0.52) FABP4FABP5RXRARXRBRXRG
SCHEMBL15375470 0.86 RXRA (0.45) FABP4FABP5RXRARXRBRXRG
SCHEMBL15375328 0.86 FABP4 (0.57) FABP4FABP5SLC1A5PTGDR2SMN1; SMN2
SCHEMBL15375371 0.86 FABP4 (0.57) FABP4FABP5SLC1A5RECQLCYP1A2
SCHEMBL15402252 0.85 ALDH1A1 (0.47) FABP4FABP5RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed