Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15375447 | 0.87 | FABP4 (0.57) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL8305675 | 0.86 | TDP1 (0.47) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL8897564 | 0.85 | FABP4 (0.61) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL28038053 | 0.81 | RXRA (0.45) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL9051241 | 0.80 | RXRA (0.46) | RXRARXRBRXRGFABP4FABP5 | |
| SCHEMBL15375521 | 0.80 | RXRA (0.46) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL15614303 | 0.80 | CDK4 (0.44) | RXRARXRBRXRGFFAR4TDP1 | |
| SCHEMBL28038060 | 0.79 | RXRA (0.43) | RXRARXRBRXRGSLC1A5FABP4 | |
| SCHEMBL15375470 | 0.79 | RXRA (0.45) | RXRARXRBRXRGFABP4FABP5 | |
| SCHEMBL15375537 | 0.79 | TDP1 (0.52) | RXRARXRBRXRGSLC1A5FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022870-A | 4-(HETEROCYCLE-SUBSTITUTED-PHENYL)-1,2,4-TRIAZOL-3-ONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0729461-B1 | FUNGICIDAL CYCLIC AMIDES | DU PONT (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5977149-A | Dihydrotriazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1996036615-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |
| EP-0729461-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014009-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |