SCHEMBL15375596

SCHEMBL15375596

COC(=O)C(O)c1ccccc1COc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
PTPRC P08575 1/20 0.44
PTPN1 P18031 1/20 0.44
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CAPN1 P07384 1/20 0.41
MAOB P27338 3/20 0.41
NR4A2 P43354 1/20 0.41
RAB9A P51151 2/20 0.41
MAOA P21397 1/20 0.40
NPC1 O15118 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
MTNR1A P48039 3/20 0.40
MTNR1B P49286 3/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375350 0.90 MAOB (0.45) LTA4HPTPRCPTPN1MAPTALDH1A1
SCHEMBL15375433 0.88 LTA4H (0.47) LTA4HSMN1; SMN2KDM4EMAPTRAB9A
SCHEMBL15402157 0.88 RXRA (0.45) LTA4HKDM4EALDH1A1MAOBNR4A2
SCHEMBL15375399 0.87 SMN1; SMN2 (0.47) SMN1; SMN2MAPTMAOBRAB9AKMT2A
SCHEMBL15402289 0.87 KMT2A (0.48) LTA4HSMN1; SMN2KDM4EMAPTALDH1A1
SCHEMBL15401969 0.86 MAPT (0.40) LTA4HSMN1; SMN2KDM4EMAPTALDH1A1
SCHEMBL15402163 0.86 MAOB (0.41) LTA4HMAOB
SCHEMBL16458088 0.84 FABP4 (0.53) SMN1; SMN2KDM4EPTPRCPTPN1MAPT
SCHEMBL15375495 0.84 MEN1 (0.44) LTA4HSMN1; SMN2KDM4EPTPRCPTPN1
SCHEMBL15375381 0.83 MAPT (0.45) SMN1; SMN2KDM4EMAPTALDH1A1FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA LTA4H 4078/4885SMN1; SMN2 4638/4885KDM4E 2619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.