SCHEMBL15375433

SCHEMBL15375433

CCc1ccc(OCc2ccccc2C(O)C(=O)OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
RAB9A P51151 4/20 0.47
NPC1 O15118 3/20 0.47
HSP90AA1 P07900 1/20 0.47
MAPT P10636 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
FFAR4 Q5NUL3 3/20 0.43
FFAR1 O14842 2/20 0.43
SCN9A Q15858 1/20 0.42
KMT2A Q03164 2/20 0.42
PPARG P37231 2/20 0.42
OPRM1 P35372 2/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
OPRL1 P41146 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
EPOR P19235 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375596 0.88 LTA4H (0.46) LTA4HRAB9ANPC1MAPTKMT2A
SCHEMBL15375350 0.87 MAOB (0.45) LTA4HRAB9ANPC1MAPTFFAR4
SCHEMBL15401872 0.86 RXRA (0.44) LTA4HRAB9ANPC1HSP90AA1MAPT
SCHEMBL15375443 0.86 SCN9A (0.48) RAB9ANPC1HSP90AA1MAPTL3MBTL1
SCHEMBL15402157 0.85 RXRA (0.45) LTA4HRAB9ANPC1L3MBTL1RXRA
SCHEMBL15402607 0.84 ADRB2 (0.38) LTA4HRAB9AMAPTFFAR4KMT2A
SCHEMBL15401894 0.84 ADRB2 (0.38) RAB9AMAPTFFAR4FFAR1KDM4E
SCHEMBL15402289 0.84 KMT2A (0.48) LTA4HRAB9ANPC1MAPTRXRA
SCHEMBL15401843 0.83 FABP4 (0.44) LTA4HRAB9AMAPTL3MBTL1KMT2A
SCHEMBL15375381 0.83 MAPT (0.45) MAPTL3MBTL1KMT2AKDM4EADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA LTA4H 4078/4885RAB9A 1780/4885NPC1 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.