SCHEMBL15375608

SCHEMBL15375608

CC(C)c1ccc(OCc2ccccc2C(O)C(N)=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
SCN9A Q15858 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
ALOX5 P09917 1/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
PARP10 Q53GL7 3/20 0.43
MAOB P27338 3/20 0.43
MAOA P21397 1/20 0.43
PARP15 Q460N3 1/20 0.43
PARP14 Q460N5 1/20 0.43
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375258 0.88 RXRA (0.50) RXRARXRBMRGPRX4ALOX5NPC1
SCHEMBL15375571 0.86 PARP10 (0.47) SCN9ANPC1RAB9AKDM4EPARP10
SCHEMBL15375524 0.86 KDM4E (0.50) SCN9AKDM4EPARP10MAOBPARP15
SCHEMBL15402157 0.86 RXRA (0.45) RXRARXRBMRGPRX4NPC1RAB9A
SCHEMBL15402278 0.85 RAB9A (0.45) RXRARXRBMRGPRX4NPC1RAB9A
SCHEMBL15375443 0.84 SCN9A (0.48) RXRARXRBSCN9ANPC1RAB9A
SCHEMBL15375394 0.83 NR4A2 (0.45) RXRARXRBSCN9ANPC1RAB9A
SCHEMBL15375481 0.83 FABP4 (0.37) RXRANPC1KDM4E
SCHEMBL13160062 0.81 RXRA (0.45) RXRARXRBMRGPRX4NPC1RAB9A
SCHEMBL15375554 0.81 FABP4 (0.44) SCN9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA RXRA 1438/4885RXRB 2062/4885SCN9A 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.