SCHEMBL15375481

SCHEMBL15375481

CC(C)c1ccc(C(C)C)c(OCc2ccccc2C(O)C(N)=O)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.37
FABP5 Q01469 1/20 0.37
BCHE P06276 4/20 0.36
ACHE P22303 4/20 0.36
GLRA1 P23415 1/20 0.35
LPAR1 Q92633 1/20 0.35
RXRA P19793 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CFD P00746 1/20 0.34
F11 P03951 1/20 0.34
TPSB2 P20231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375542 0.89 FABP4 (0.48) FABP4FABP5BCHEACHEGLRA1
SCHEMBL15375554 0.87 FABP4 (0.44) FABP4FABP5MEN1KMT2AKDM4E
SCHEMBL15402604 0.87 BCHE (0.38) FABP4FABP5BCHEACHEGLRA1
SCHEMBL15375348 0.86 TSHR (0.37) BCHEACHELPAR1KDM4EALDH1A1
SCHEMBL15401766 0.86 BCHE (0.42) FABP4FABP5BCHEACHEMEN1
SCHEMBL15375608 0.83 RXRA (0.46) RXRANPC1KDM4E
SCHEMBL15401949 0.80 PTGDR2 (0.44) FABP4FABP5LPAR1MEN1KMT2A
SCHEMBL15375400 0.80 FABP4 (0.44) FABP4FABP5GLRA1MEN1KMT2A
SCHEMBL1539382 0.80 NISCH (0.36) FABP4FABP5BCHEACHEGLRA1
SCHEMBL15375398 0.80 ACHE (0.34) BCHEACHERXRAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA FABP4 4349/4885FABP5 4435/4885BCHE 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.