Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282674 | 0.88 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL15566368 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL16901934 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL15566993 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL15596841 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL27966918 | 0.79 | NPBWR1 (0.40) | SMN1; SMN2LMNANPSR1NPBWR1MCHR1 | |
| SCHEMBL10927755 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL21511152 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL16901906 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNANPSR1ATMHPGD | |
| SCHEMBL18672266 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPSR1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| EP-2692723-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2014-02-05 | — | — | EP | disclosed |
| EP-2692723-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2014-02-05 | — | — | EP | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | DDT, CYP4B1, AADAC | SMN1; SMN2 4003/4885LMNA 4489/4885NPSR1 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.