Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998536 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL10366104 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL18672266 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL1627210 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL21720358 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL21442599 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL8282674 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL16895310 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTATMHPGD | |
| SCHEMBL466352 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2ATMHPGDNPSR1RAB9A | |
| SCHEMBL17738012 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257315-B1 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING INC (US) | 2019-10-23 | — | — | EP | disclosed |