SCHEMBL15399050

SCHEMBL15399050

CC(C)(C)c1cc(CCN=C=O)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 5/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 2/20 0.37
LMNA P02545 3/20 0.35
MAOB P27338 3/20 0.35
MAOA P21397 2/20 0.35
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 1/20 0.34
F2R P25116 1/20 0.33
ACHE P22303 1/20 0.33
TSHR P16473 1/20 0.33
AGTR1 P30556 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590186 0.89 NPC1 (0.38) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL3691311 0.85 NPC1 (0.40) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL75075 0.82 NPC1 (0.44) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL30240935 0.82 NPC1 (0.44) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL13324689 0.82 NPC1 (0.44) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL10135977 0.81 GAA (0.44) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL29768287 0.81 MAOB (0.45) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL9324329 0.81 NPC1 (0.40) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL100766 0.81 MAOB (0.45) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL2955109 0.80 NPC1 (0.42) NPC1RAB9AGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3471694-B1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS KENVUE BRANDS LLC (US) 2025-07-02 EP disclosed
US-12303580-B2 Sunscreen compositions containing a combination of a linear ultraviolet radiation-absorbing polyether and other ultraviolet-screening compounds KENVUE BRANDS LLC (US) 2025-05-20 US disclosed
US-20220280400-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS KENVUE BRANDS LLC 2022-09-08 US disclosed
US-20190175468-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS JOHNSON & JOHNSON CONSUMER INC. 2019-06-13 US disclosed
US-20190175468-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS JOHNSON & JOHNSON CONSUMER INC. 2019-06-13 US disclosed
US-10278910-B2 Sunscreen compositions containing an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER INC. (US) 2019-05-07 US disclosed
US-10278910-B2 Sunscreen compositions containing an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER INC. (US) 2019-05-07 US disclosed
EP-3471694-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS Johnson & Johnson Consumer Inc. (US) 2019-04-24 EP disclosed
EP-2679616-B1 Ultraviolet radiation absorbing polyethers JOHNSON & JOHNSON CONSUMER INC (US) 2018-05-16 EP disclosed
EP-2866898-B1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER INC (US) 2018-04-04 EP disclosed
EP-2866898-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS Johnson & Johnson Consumer Companies, Inc. (US) 2015-05-06 EP disclosed
EP-2866899-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER Johnson & Johnson Consumer Companies, Inc. (US) 2015-05-06 EP disclosed
WO-2014004477-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
WO-2014004176-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
WO-2014004474-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
WO-2014004176-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER KENVUE BRANDS LLC 2014-01-02 US disclosed
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US disclosed
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US disclosed
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190175468-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS ERCC4, ERCC1, ERCC5 NPC1 1402/4885RAB9A 2609/4885GAA 951/4885
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS ERCC4, XRCC6, PUF60 NPC1 1638/4885RAB9A 2510/4885GAA 1531/4885
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS PARG, PARN, PUF60 NPC1 1435/4885RAB9A 3103/4885GAA 76/4885
US-20220280400-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS ERCC4, ERCC1, ERCC5 NPC1 1402/4885RAB9A 2609/4885GAA 951/4885
US-12303580-B2 Sunscreen compositions containing a combination of a linear ultraviolet radiation-absorbing polyether and other ultraviolet-screening compounds ERCC4, ERCC1, ERCC5 NPC1 1402/4885RAB9A 2609/4885GAA 951/4885
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER PCNA, SUN2, TTPA NPC1 808/4885RAB9A 3493/4885GAA 1752/4885
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER MMS19, SUN2, ERCC1 NPC1 1101/4885RAB9A 2957/4885GAA 1112/4885
US-10278910-B2 Sunscreen compositions containing an ultraviolet radiation-absorbing polymer MMS19, SUN2, ERCC1 NPC1 1101/4885RAB9A 2957/4885GAA 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.