Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | CYCS | P99999 | 4/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.47 |
| ▸ | PDE2A | O00408 | 3/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831938 | 0.81 | PPARG (0.51) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL19718136 | 0.81 | PPARG (0.51) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL3554346 | 0.81 | TOP1 (0.48) | TOP1CYCSPDE3BPDE3APDE2A | |
| SCHEMBL29831314 | 0.80 | PPARG (0.52) | CYCSPDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL19718153 | 0.80 | PPARG (0.52) | CYCSPDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL6850253 | 0.75 | PDE3B (0.45) | TOP1CYCSPDE3BPDE3AP2RY12 | |
| SCHEMBL6851842 | 0.75 | PDE3B (0.45) | TOP1CYCSPDE3BPDE3AP2RY12 | |
| SCHEMBL6847497 | 0.75 | PDE3B (0.45) | TOP1CYCSPDE3BPDE3AP2RY12 | |
| SCHEMBL6851379 | 0.75 | PDE3B (0.45) | TOP1CYCSPDE3BPDE3AP2RY12 | |
| SCHEMBL7614765 | 0.75 | FABP4 (0.53) | TOP1CYCSPDE3BPDE3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555132-B2 | Water-soluble nanoparticles | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-01-31 | — | — | US | disclosed |
| US-20140004048-A1 | WATER-SOLUBLE NANOPARTICLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2014-01-02 | — | — | US | disclosed |