Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15399779 | 0.81 | TOP1 (0.49) | TOP1CYCSABCG2PDE3BPDE3A | |
| SCHEMBL30567312 | 0.79 | TERT (0.49) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3794157 | 0.78 | TOP1 (0.61) | TOP1CYCSABCG2PDE3BPDE3A | |
| SCHEMBL29558419 | 0.78 | TOP1 (0.61) | TOP1CYCSABCG2PDE3BPDE3A | |
| SCHEMBL2531376 | 0.77 | TERT (0.49) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL8031578 | 0.77 | TERT (0.49) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL12190732 | 0.77 | TERT (0.49) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL28675056 | 0.76 | TOP1 (0.47) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL12057399 | 0.76 | ENPP2 (0.46) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL12633085 | 0.75 | TERT (0.47) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649091-B2 | complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers | EUKARION, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20060241095-A1 | Orally bioavailable low molecular weight metalloporphyrins as antioxidants | EUKARION, INC. | 2006-10-26 | — | — | US | disclosed |
| EP-1631572-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005000854-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241095-A1 | Orally bioavailable low molecular weight metalloporphyrins as antioxidants | SLC40A1, HMOX1, SOD1 | TOP1 2805/4885CYCS 586/4885ABCG2 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.