Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 1.00 |
| ▸ | MMP8 | P22894 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31496761 | 0.99 | MMP2 (0.98) | MMP2MMP8HRH1ELOVL1NPC1 | |
| SCHEMBL30772150 | 0.93 | MMP2 (0.86) | MMP2MMP8HRH1ELOVL1NPC1 | |
| SCHEMBL27821015 | 0.90 | MMP2 (0.82) | MMP2MMP8HRH1NPC1ACHE | |
| SCHEMBL30772148 | 0.90 | MMP2 (0.82) | MMP2MMP8HRH1ELOVL1NPC1 | |
| SCHEMBL24993420 | 0.90 | MMP2 (0.82) | MMP2MMP8HRH1ELOVL1NPC1 | |
| SCHEMBL24993421 | 0.89 | MMP2 (0.80) | MMP2MMP8ELOVL1NPC1KMT2A | |
| SCHEMBL27235580 | 0.88 | MMP2 (0.78) | MMP2MMP8NPC1ACHEKMT2A | |
| SCHEMBL30173490 | 0.88 | MMP2 (0.78) | MMP2MMP8NPC1ACHEKMT2A | |
| Hydrochloric Acid SCHEMBL31496774 | 0.85 | MMP2 (0.74) | MMP2MMP8ELOVL1NPC1ACHE | |
| SCHEMBL15403403 | 0.80 | ACHE (0.74) | MMP2MMP8ACHEKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661467-A | Synthesis process of N- (4-phenylthiazole-2-yl) -3- (4-benzylpiperazine-1-yl) propionamide monohydrochloride | 武汉亿诺药业有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-115944635-B | Application of aminothiazole derivative in preparation of immunity inflammation medicine | 宁波亿诺药业有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-118903134-A | Application of aminothiazole derivative in preparation of drug for treating alcoholic liver disease | 武汉亿诺药业有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118903135-A | Application of aminothiazole derivative in preparation of medicine for treating diseases caused by high-fat diet | 武汉亿诺药业有限公司 | 2024-11-08 | — | — | CN | claimed |
| US-20240180898-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN TREATMENT OF IMMUNE INFLAMMATION | INNAMUNE PHARMACEUTICAL CO. LTD. (CN) | 2024-06-06 | — | — | US | claimed |
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | claimed |
| EP-3424912-B1 | 2-AMINOTHIAZOLE DERIVATIVES, PREPARATION AND USE THEREOF | UNIV HUAZHONG SCIENCE TECH (CN) | 2022-09-07 | — | — | EP | claimed |
| CN-119661467-A | Synthesis process of N- (4-phenylthiazole-2-yl) -3- (4-benzylpiperazine-1-yl) propionamide monohydrochloride | 武汉亿诺药业有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-115944635-B | Application of aminothiazole derivative in preparation of immunity inflammation medicine | 宁波亿诺药业有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118903135-A | Application of aminothiazole derivative in preparation of medicine for treating diseases caused by high-fat diet | 武汉亿诺药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118903134-A | Application of aminothiazole derivative in preparation of drug for treating alcoholic liver disease | 武汉亿诺药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024027807-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN PREPARING DRUG FOR IMMUNOLOGICAL INFLAMMATION | 宁波亿诺药业有限公司 | 2024-02-08 | — | — | WO | disclosed |
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-106668022-B | Application of aminothiazole MyD88 specific inhibitor TJM2010-5 | 武汉应内药业有限公司 | 2020-09-15 | — | — | CN | disclosed |
| EP-3424912-A1 | 2-AMINOTHIAZOLE DERIVATIVES FOR MEDICAL USE | Huazhong University of Science and Technology (CN) | 2019-01-09 | — | — | EP | disclosed |
| US-20180318291-A1 | USE OF AMINOTHIAZOLE MYD88 SPECIFIC INHIBITOR TJM2010-5 | WUHAN INNAMUNE PHARMACEUTICAL INC. LTD. (CN) | 2018-11-08 | — | — | US | disclosed |
| US-9771340-B2 | 2-aminothiazole derivatives and methods of preparing and using the same | WUHAN INNAMUNE PHARMACEUTICAL CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| WO-2017075845-A1 | USE OF AMINOTHIAZOLE MYD88 SPECIFIC INHIBITOR TJM2010-5 | 武汉应内药业有限公司 | 2017-05-11 | — | — | WO | disclosed |
| EP-2682390-A1 | 2-AMINOTHIAZOLE DERIVATIVE, PREPARATION METHOD, AND USE | Huazhong University of Science and Technology (CN) | 2014-01-08 | — | — | EP | disclosed |
| US-20140004155-A1 | 2-AMINOTHIAZOLE DERIVATIVES AND METHODS OF PREPARING AND USING THE SAME | HANGZHOU ZHONGMEI HUADONG PHARMACEUTICAL CO., LTD. (CN) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180318291-A1 | USE OF AMINOTHIAZOLE MYD88 SPECIFIC INHIBITOR TJM2010-5 | IRAK4, IRAK1, IRAK2 | MMP2 2989/4885MMP8 1661/4885HRH1 4006/4885 |
| US-20140004155-A1 | 2-AMINOTHIAZOLE DERIVATIVES AND METHODS OF PREPARING AND USING THE SAME | CCNT1, CCNE1, CCNT2 | MMP2 3265/4885MMP8 4190/4885HRH1 39/4885 |
| US-20240180898-A1 | USE OF AMINOTHIAZOLE DERIVATIVE IN TREATMENT OF IMMUNE INFLAMMATION | AADAT, IDO1, IDO2 | MMP2 2870/4885MMP8 1107/4885HRH1 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.