Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.78 |
| ▸ | MMP8 | P22894 | 1/20 | 0.78 |
| ▸ | MYD88 | Q99836 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.56 |
| ▸ | ATP4A | P20648 | 2/20 | 0.56 |
| ▸ | ATP4B | P51164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173490 | 1.00 | MMP2 (0.78) | MMP2MMP8MYD88ALDH1A1HPGD | |
| SCHEMBL27821015 | 0.90 | MMP2 (0.82) | MMP2MMP8MYD88ALDH1A1ACHE | |
| SCHEMBL24993420 | 0.88 | MMP2 (0.82) | MMP2MMP8MYD88ALDH1A1HPGD | |
| SCHEMBL30772148 | 0.88 | MMP2 (0.82) | MMP2MMP8MYD88ALDH1A1HPGD | |
| SCHEMBL15401374 | 0.88 | MMP2 (1.00) | MMP2MMP8MYD88ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL31496761 | 0.87 | MMP2 (0.98) | MMP2MMP8MYD88ALDH1A1HPGD | |
| SCHEMBL30772149 | 0.87 | ACHE (0.66) | MMP2MMP8ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30772150 | 0.83 | MMP2 (0.86) | MMP2MMP8MYD88ALDH1A1ACHE | |
| SCHEMBL15403403 | 0.81 | ACHE (0.74) | MMP2MMP8ALDH1A1ACHELMNA | |
| SCHEMBL27840487 | 0.81 | MAPK1 (0.73) | MMP2MMP8ALDH1A1ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115944635-A | Application of aminothiazole derivative in preparing medicine for treating immune inflammation | 宁波亿诺药业有限公司 | 2023-04-11 | — | — | CN | disclosed |