Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970820 | 1.00 | GRM5 (0.37) | GRM5CDK7BTK | |
| SCHEMBL9977728 | 0.91 | GSK3A (0.39) | GRM5 | |
| SCHEMBL15399800 | 0.91 | GSK3A (0.39) | GRM5 | |
| SCHEMBL16199061 | 0.91 | GSK3A (0.39) | GRM5 | |
| SCHEMBL9967246 | 0.88 | CDK7 (0.43) | CDK7 | |
| SCHEMBL15401369 | 0.87 | CDK7 (0.38) | GRM5CDK7 | |
| SCHEMBL9970812 | 0.87 | CDK7 (0.38) | GRM5CDK7 | |
| SCHEMBL9970823 | 0.81 | BTK (0.34) | GRM5CDK7BTK | |
| SCHEMBL15401427 | 0.80 | GSK3A (0.39) | — | |
| SCHEMBL15400659 | 0.80 | GSK3A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140005197-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005197-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, RNASEH1, ACE2 | GRM5 4805/4885CDK7 961/4885BTK 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.