Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ESRRG | P62508 | 2/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073725 | 0.89 | NPC1 (0.66) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL3237376 | 0.88 | ESRRG (0.59) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL27894530 | 0.84 | NPC1 (0.56) | LMNAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL16771933 | 0.82 | ALDH1A1 (0.60) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL1999539 | 0.81 | LMNA (0.51) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL16760266 | 0.80 | KMT2A (0.48) | LMNAGAAHPGDTDP1NPC1 | |
| SCHEMBL17991475 | 0.80 | SLC6A5 (0.54) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL30365971 | 0.80 | LMNA (0.60) | LMNAGAAHPGDTP53MAPT | |
| SCHEMBL16771863 | 0.79 | TP53 (0.49) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL1384403 | 0.79 | CNR2 (0.57) | LMNAALDH1A1KDM4EHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603128-B | Antifungal heterocycle carbonyl acid amides | 杜邦公司 | 2017-09-08 | — | — | CN | disclosed |
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2867228-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. Du Pont de Nemours and Company (US) | 2015-05-06 | — | — | EP | disclosed |
| CN-104603128-A | Fungicidal heterocyclic carboxamides | DU PONT | 2015-05-06 | — | — | CN | disclosed |
| US-8815772-B2 | Fungicidal heterocyclic carboxamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2014004064-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-03 | — | — | WO | disclosed |
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | FMC CORPORATION | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | CBR3, CBR1, NOX3 | LMNA 1253/4885GAA 759/4885ALDH1A1 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.