Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859256 | 0.80 | NPC1 (0.73) | NPC1RAB9ATP53MAPTKMT2A | |
| SCHEMBL5676692 | 0.71 | MALT1 (0.60) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL6098089 | 0.70 | MAPT (0.50) | TP53MAPTKMT2AHPGDKDM4E | |
| SCHEMBL6096249 | 0.68 | MAPT (0.51) | TP53MAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL27582575 | 0.68 | KLKB1 (0.57) | TP53MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL2860256 | 0.68 | CNR1 (0.58) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6098368 | 0.67 | MAPT (0.50) | MAPTHPGDALDH1A1 | |
| SCHEMBL2859054 | 0.67 | POLB (0.71) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13753976 | 0.67 | KDM4E (0.69) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5717760 | 0.67 | MAPT (0.52) | NPC1RAB9ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | claimed |
| US-8815772-B2 | Fungicidal heterocyclic carboxamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | claimed |
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | FMC CORPORATION | 2014-01-02 | — | — | US | claimed |
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2867228-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. Du Pont de Nemours and Company (US) | 2015-05-06 | — | — | EP | disclosed |
| US-8815772-B2 | Fungicidal heterocyclic carboxamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2014004064-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-03 | — | — | WO | disclosed |
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | FMC CORPORATION | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005231-A1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | CBR3, CBR1, NOX3 | NPC1 1461/4885RAB9A 289/4885TP53 4624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.