SCHEMBL15401683

SCHEMBL15401683

CCc1ccc(OCc2ccccc2C(O)C(=O)NC)c(CC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 2/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
KDM4E B2RXH2 2/20 0.38
FABP4 P15090 1/20 0.37
FABP5 Q01469 1/20 0.37
FFAR4 Q5NUL3 4/20 0.36
FOLH1 Q04609 1/20 0.36
AKT1 P31749 1/20 0.36
PPARG P37231 3/20 0.36
PPARD Q03181 3/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
PPARA Q07869 2/20 0.36
FFAR1 O14842 1/20 0.35
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15401820 0.91 FABP4 (0.37) KDM4EFABP4FABP5FFAR4FOLH1
SCHEMBL15402835 0.88 MAPT (0.44) KDM4EFABP4FABP5MAPTTHRB
SCHEMBL15401894 0.87 ADRB2 (0.38) KDM4EFABP4FABP5FFAR4FOLH1
SCHEMBL15375491 0.87 FABP4 (0.49) FABP4FABP5FFAR4FOLH1PPARG
SCHEMBL15402673 0.86 FABP4 (0.40) OPRK1OPRM1OPRD1KDM4EFABP4
SCHEMBL15375597 0.86 CYP2D6 (0.44) KDM4EFABP4FABP5FFAR4FOLH1
SCHEMBL15401872 0.84 RXRA (0.44) OPRK1OPRM1OPRD1KDM4EFFAR4
SCHEMBL15402594 0.80 FABP4 (0.43) KDM4EFABP4FABP5MAPTTHRB
SCHEMBL15402116 0.80 MRGPRX4 (0.44) FFAR4MAPTPOLBALDH1A1RAB9A
SCHEMBL15402172 0.80 MAPT (0.43) FABP4FABP5FFAR4MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA OPRK1 793/4885OPRM1 1075/4885OPRD1 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.