SCHEMBL15401872

SCHEMBL15401872

CCc1ccc(OCc2ccccc2C(O)C(=O)NC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
PPARG P37231 2/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
HSP90AA1 P07900 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
FFAR4 Q5NUL3 2/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SCN9A Q15858 1/20 0.41
KMT2A Q03164 3/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375495 0.88 MEN1 (0.44) RAB9ANPC1MMP9MMP8MAPT
SCHEMBL15401828 0.87 MEN1 (0.46) RAB9ANPC1MMP9MMP8FFAR4
SCHEMBL15375433 0.86 LTA4H (0.47) RXRARXRBPPARGRAB9ANPC1
SCHEMBL15402114 0.85 RAB9A (0.44) RXRARXRBPPARGRAB9ANPC1
SCHEMBL15402278 0.85 RAB9A (0.45) RXRARXRBPPARGRAB9ANPC1
SCHEMBL15375443 0.85 SCN9A (0.48) RXRARXRBRAB9ANPC1HSP90AA1
SCHEMBL15401683 0.84 OPRK1 (0.39) PPARGRAB9AFFAR4FFAR1MAPT
SCHEMBL15401820 0.84 FABP4 (0.37) PPARGRAB9AFFAR4MAPTL3MBTL1
SCHEMBL15401870 0.84 POLB (0.44) RXRARXRBRAB9ANPC1MAPT
SCHEMBL15402594 0.83 FABP4 (0.43) MAPTL3MBTL1KMT2AKCNH2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA RXRA 1438/4885RXRB 2062/4885PPARG 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.