SCHEMBL15401766

SCHEMBL15401766

CNC(=O)C(O)c1ccccc1COc1cc(C(C)C)ccc1C(C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.42
ACHE P22303 3/20 0.42
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 2/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15401423 0.88 LMNA (0.43) FABP4FABP5MEN1KMT2AALDH1A1
SCHEMBL15402604 0.87 BCHE (0.38) BCHEACHEFABP4FABP5MEN1
SCHEMBL15375542 0.87 FABP4 (0.48) BCHEACHEFABP4FABP5KMT2A
SCHEMBL15401610 0.87 BCHE (0.40) BCHEACHEFABP4FABP5MEN1
SCHEMBL15375316 0.87 BCHE (0.40) BCHEACHEMEN1KMT2AALDH1A1
SCHEMBL15375481 0.86 FABP4 (0.37) BCHEACHEFABP4FABP5MEN1
SCHEMBL15402278 0.83 RAB9A (0.45) MEN1KMT2ANPC1MAPTALDH1A1
SCHEMBL15375528 0.81 LPAR1 (0.42) FABP4FABP5KMT2A
SCHEMBL15403550 0.81 FABP4 (0.43) FABP4FABP5
SCHEMBL15402835 0.79 MAPT (0.44) FABP4FABP5MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA BCHE 2680/4885ACHE 1848/4885FABP4 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.