SCHEMBL15401949

SCHEMBL15401949

CC(C)c1ccccc1OCc1cc(Cl)ccc1C(O)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.44
LPAR1 Q92633 4/20 0.43
KDM4E B2RXH2 1/20 0.42
FABP4 P15090 3/20 0.41
FABP5 Q01469 3/20 0.41
FABP3 P05413 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38
PTGER1 P34995 2/20 0.37
HDAC8 Q9BY41 1/20 0.37
EPHX1 P07099 1/20 0.37
NISCH Q9Y2I1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375348 0.87 TSHR (0.37) PTGDR2LPAR1KDM4EMRGPRX4HDAC8
SCHEMBL15401433 0.87 LPAR1 (0.45) PTGDR2LPAR1FABP4FABP5FABP3
SCHEMBL15402040 0.87 PTGDR2 (0.53) PTGDR2KDM4EFABP4FABP5FABP3
SCHEMBL15402016 0.87 PTGDR2 (0.50) PTGDR2KDM4EFABP4FABP5FABP3
SCHEMBL15375554 0.86 FABP4 (0.44) KDM4EFABP4FABP5MEN1KMT2A
SCHEMBL15375528 0.86 LPAR1 (0.42) PTGDR2LPAR1FABP4FABP5FABP3
SCHEMBL15375481 0.80 FABP4 (0.37) LPAR1KDM4EFABP4FABP5MEN1
SCHEMBL15375550 0.80 SGMS2 (0.41) PTGDR2LPAR1FABP4FABP5MRGPRX4
SCHEMBL15401875 0.79 PTGDR2 (0.49) PTGDR2MRGPRX4MEN1KMT2A
SCHEMBL15402168 0.78 KDM4E (0.41) PTGDR2KDM4EFABP4FABP5FABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA PTGDR2 938/4885LPAR1 3283/4885KDM4E 2619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.