SCHEMBL15401968

SCHEMBL15401968

CNC(=O)C(OC)c1ccccc1COc1cc(C)c(C)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MAOB P27338 1/20 0.39
FABP4 P15090 1/20 0.38
FABP5 Q01469 1/20 0.38
CD274 Q9NZQ7 13/20 0.38
POLB P06746 2/20 0.36
ESR1 P03372 1/20 0.35
TP53 P04637 1/20 0.35
APEX1 P27695 1/20 0.35
MAPK1 P28482 1/20 0.35
ESR2 Q92731 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
FFAR1 O14842 1/20 0.35
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402296 0.90 ALDH1A1 (0.40) LMNAFABP4FABP5TP53TDP1
SCHEMBL15375322 0.87 FABP4 (0.44) LMNAMAOBFABP4FABP5POLB
SCHEMBL15402061 0.86 MEN1 (0.44) LMNAMAOBFABP4FABP5POLB
SCHEMBL7969296 0.86 MEN1 (0.42) LMNAFABP4FABP5MAPK1L3MBTL1
SCHEMBL15402468 0.86 SMN1; SMN2 (0.45) MAOBMAPK1
SCHEMBL15401831 0.85 MAOB (0.40) MAOBCD274POLBESR1TP53
SCHEMBL28038430 0.85 FABP4 (0.36) LMNAMAOBFABP4FABP5CD274
SCHEMBL15402165 0.84 FABP4 (0.42) LMNAFABP4FABP5CD274FFAR1
SCHEMBL15402300 0.84 FABP4 (0.42) LMNAFABP4FABP5POLBTDP1
SCHEMBL15402214 0.84 FABP4 (0.46) LMNAMAOBFABP4FABP5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA LMNA 4708/4885MAOB 1169/4885FABP4 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.