SCHEMBL15375322

SCHEMBL15375322

CNC(=O)C(OC)c1ccccc1COc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.44
FABP5 Q01469 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 4/20 0.42
KDM4E B2RXH2 1/20 0.42
PTPRC P08575 1/20 0.41
PTPN1 P18031 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
ALDH1A1 P00352 2/20 0.40
LTA4H P09960 1/20 0.40
POLB P06746 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
CAPN1 P07384 1/20 0.39
MAOB P27338 3/20 0.39
NR4A2 P43354 1/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402061 0.91 MEN1 (0.44) FABP4FABP5MEN1KMT2ASMN1; SMN2
SCHEMBL15402176 0.89 RAB9A (0.43) FABP4FABP5MEN1KMT2AKDM4E
SCHEMBL15402114 0.89 RAB9A (0.44) MEN1KMT2ASMN1; SMN2KDM4ERAB9A
SCHEMBL15402468 0.88 SMN1; SMN2 (0.45) MEN1KMT2ASMN1; SMN2RAB9AMAOB
SCHEMBL15402310 0.88 NPC1 (0.43) MEN1KMT2ASMN1; SMN2KDM4ELMNA
SCHEMBL15401968 0.87 LMNA (0.41) FABP4FABP5LMNAPOLBMAOB
SCHEMBL15402296 0.87 ALDH1A1 (0.40) FABP4FABP5MEN1KMT2ASMN1; SMN2
SCHEMBL28038430 0.84 FABP4 (0.36) FABP4FABP5MEN1KMT2AKDM4E
SCHEMBL15402000 0.84 FABP4 (0.47) FABP4FABP5MEN1KMT2ASMN1; SMN2
SCHEMBL15403047 0.84 FABP4 (0.47) FABP4FABP5MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA FABP4 4349/4885FABP5 4435/4885MEN1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.