Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15410865 | 0.83 | CYP11B2 (0.49) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL15412101 | 0.81 | ESRRG (0.44) | KMT2AGAAGPR27NTRK1MEN1 | |
| SCHEMBL15411326 | 0.81 | RXFP1 (0.40) | KMT2AALDH1A1SMN1; SMN2NTRK1MEN1 | |
| SCHEMBL15410038 | 0.80 | TSHR (0.51) | NPC1RAB9AALDH1A1TMPRSS4GPR35 | |
| SCHEMBL15411825 | 0.80 | KMT2A (0.52) | KMT2AALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL15410721 | 0.80 | MEN1 (0.56) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL15410034 | 0.80 | KCNJ11 (0.47) | NPC1RAB9AKMT2ALMNATP53 | |
| SCHEMBL15410723 | 0.78 | KCNJ11 (0.52) | NPC1RAB9AKMT2AALDH1A1GAA | |
| SCHEMBL15410162 | 0.76 | SMN1; SMN2 (0.46) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL3853307 | 0.76 | SMN1; SMN2 (0.70) | NPC1RAB9AKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | AHR, DDT, AOC2 | NPC1 2304/4885RAB9A 661/4885KMT2A 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.