Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15410493 | 0.84 | TSHR (0.42) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL15409614 | 0.84 | RAB9A (0.52) | KCNJ11RAB9ATP53NPC1MEN1 | |
| SCHEMBL15410033 | 0.84 | NPC1 (0.54) | KCNJ11RAB9ATP53NPC1MEN1 | |
| SCHEMBL15410726 | 0.83 | TRPV1 (0.59) | RAB9ATP53NPC1MEN1KMT2A | |
| SCHEMBL15410723 | 0.82 | KCNJ11 (0.52) | KCNJ11RAB9ATP53NPC1MEN1 | |
| SCHEMBL15409617 | 0.81 | TSHR (0.56) | KCNJ11RAB9ATP53NPC1MAPK1 | |
| SCHEMBL15411234 | 0.81 | MLYCD (0.55) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL15411337 | 0.80 | NPC1 (0.53) | RAB9ATP53NPC1MEN1KMT2A | |
| SCHEMBL14716260 | 0.77 | TSHR (0.56) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL19097365 | 0.76 | HPGD (0.49) | RAB9ANPC1KMT2AMAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | AHR, DDT, AOC2 | KCNJ11 1353/4885RAB9A 661/4885TP53 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.