Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25186704 | 0.88 | GRIN1 (0.65) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL15672787 | 0.88 | GRIN1 (0.65) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL15412346 | 0.88 | GRIN1 (0.65) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL25189601 | 0.88 | GRIN1 (0.65) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL3118670 | 0.88 | GRIN1 (0.65) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL12478797 | 0.84 | G6PD (0.61) | G6PDCYP3A4PMP22KMT2ACYP1A2 | |
| SCHEMBL25326883 | 0.83 | LMNA (0.59) | CYP3A4KMT2ACYP1A2CYP2C9TSHR | |
| SCHEMBL25323572 | 0.83 | LMNA (0.59) | CYP3A4KMT2ACYP1A2CYP2C9TSHR | |
| SCHEMBL25322998 | 0.83 | LMNA (0.59) | CYP3A4KMT2ACYP1A2CYP2C9TSHR | |
| SCHEMBL25912307 | 0.83 | LMNA (0.59) | CYP3A4KMT2ACYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160317556-A1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | SOCPRA SCIENCES ET GENIE S.E.C. | 2016-11-03 | — | — | US | claimed |
| US-10716797-B2 | Steroid alkaloids and compositions and kits thereof | SOCPRA SCIENCES ET GÉNIE S.E.C. (CA) | 2020-07-21 | — | — | US | disclosed |
| US-20190008875-A1 | STEROID ALKALOIDS AND COMPOSITIONS AND KITS THEREOF | UNIVERSITé DE SHERBROOKE (CA) | 2019-01-10 | — | — | US | disclosed |
| US-10137137-B2 | ATP synthase inhibitors and steroid alkaloids and uses thereof as antimicrobial agents and as potentiators for aminoglycosides against pathogenic bacteria | SOCPRA SCIENCES ET GENIE S.E.C. (CA) | 2018-11-27 | — | — | US | disclosed |
| US-20160317556-A1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | SOCPRA SCIENCES ET GENIE S.E.C. | 2016-11-03 | — | — | US | disclosed |
| US-9457033-B2 | Steroid alkaloids and uses thereof as antimicrobial agents against electron transport-deficient microbes and as potentiators for antimicrobial agents against pathogenic bacteria | SOCPRA SCIENCES ET GENIE, S.E.C. (CA) | 2016-10-04 | — | — | US | disclosed |
| US-20140018312-A1 | STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AGAINST ELECTRON TRANSPORT-DEFICIENT MICROBES AND AS POTENTIATORS FOR ANTIMICROBIAL AGENTS AGAINST PATHOGENIC BACTERIA | SOCPRA SCIENCES ET GENIE, S.E.C. (CA) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018312-A1 | STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AGAINST ELECTRON TRANSPORT-DEFICIENT MICROBES AND AS POTENTIATORS FOR ANTIMICROBIAL AGENTS AGAINST PATHOGENIC BACTERIA | TOMM70, TIMM50, TIMM10 | G6PD 1199/4885CYP3A4 1222/4885PMP22 1785/4885 |
| US-20160317556-A1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | ATP5ME, ATP5MG, ATP5F1A | G6PD 438/4885CYP3A4 506/4885PMP22 3125/4885 |
| US-20190008875-A1 | STEROID ALKALOIDS AND COMPOSITIONS AND KITS THEREOF | ATP5ME, ATP5MG, ATP5F1A | G6PD 1321/4885CYP3A4 405/4885PMP22 3245/4885 |
| US-10137137-B2 | ATP synthase inhibitors and steroid alkaloids and uses thereof as antimicrobial agents and as potentiators for aminoglycosides against pathogenic bacteria | ATP5ME, ATP5MG, ATP5F1A | G6PD 438/4885CYP3A4 506/4885PMP22 3125/4885 |
| US-10716797-B2 | Steroid alkaloids and compositions and kits thereof | ATP5ME, ATP5MG, ATP5F1A | G6PD 1321/4885CYP3A4 405/4885PMP22 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.