Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412657 | 0.88 | PPARA (0.44) | MAPTALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL15412609 | 0.81 | MAPT (0.44) | MAPTALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL27619302 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL23685780 | 0.78 | PPARA (0.41) | MAPTALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL27790888 | 0.70 | CA12 (0.55) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL7218237 | 0.70 | MAPT (0.74) | MAPTALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL23685927 | 0.69 | MAPT (0.38) | MAPTALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL6024348 | 0.68 | EGFR (0.49) | MAPTALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL8985829 | 0.67 | CA12 (0.58) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL15413120 | 0.66 | KMT2A (0.48) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872489-B1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-9512080-B2 | Synthesis of acridinium compounds by N-alkylation of acridans | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150197491-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-07-16 | — | — | US | disclosed |
| EP-2872489-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | Siemens Healthcare Diagnostics Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011762-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | SIEMENS HEAL THCARE DIAGNOSTICS INC. (US) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197491-A1 | SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS | ACR, MCL1, MGMT | MAPT 4190/4885ALDH1A1 315/4885L3MBTL1 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.