SCHEMBL6024348

SCHEMBL6024348

COC(=O)C1c2ccccc2Nc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.49
MAPT P10636 10/20 0.48
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 6/20 0.47
TDP1 Q9NUW8 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
NLRP3 Q96P20 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
BACE1 P56817 1/20 0.40
HTT P42858 1/20 0.40
ITGA4 P13612 1/20 0.39
ATM Q13315 1/20 0.39
ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7681777 0.88 MAPT (0.58) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL6882114 0.81 CHRNB2 (0.39) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL27619302 0.81 ALDH1A1 (0.62) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL27487537 0.79 CYP1A2 (0.46) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL106257 0.79 HDAC4 (0.57) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL5803188 0.76 PDE5A (0.37) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL2995499 0.76 ALDH1A1 (0.53) EGFRMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL15412657 0.76 PPARA (0.44) EGFRMAPTALDH1A1L3MBTL1KDM4E
Bromomethane SCHEMBL4427405 0.76 HDAC4 (0.53) MAPTALDH1A1MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL2986141 0.75 ALDH1A1 (0.51) EGFRMAPTALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494396-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF Pierce Biotechnology, Inc. (US) 2019-06-12 EP claimed
WO-2018027004-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. (US) 2018-02-08 WO claimed
US-10722882-B2 Chemiluminescent and fluorescent substrate pads and uses thereof PIERCE BIOTECHNOLOGY, INC. (US) 2020-07-28 US disclosed
EP-3494396-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF Pierce Biotechnology, Inc. (US) 2019-06-12 EP disclosed
US-20180043355-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. 2018-02-15 US disclosed
WO-2018027004-A1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY, INC. (US) 2018-02-08 WO disclosed
CN-1659278-B Fluorescent detection of peroxidase enzymes LUMIGEN INC 2014-07-09 CN disclosed
EP-1353908-B1 PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES LUMIGEN INC (US) 2006-03-08 EP disclosed
EP-1353908-A4 PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES LUMIGEN INC (US) 2004-01-28 EP disclosed
EP-1353908-A1 PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES LUMIGEN, INC. (US) 2003-10-22 EP disclosed
WO-2002059096-A1 PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES LUMIGEN, INC. (US) 2002-08-01 WO disclosed
US-6410732-B2 FORMATION OF BOND BETWEEN NITROGEN ATOM OF ACRIDAN RING AND CARBON ATOM OF ANOTHER AROMATIC OR HETEROAROMATIC RING COMPOUND; ASSAYS FOR PEROXIDASE ENZYMES AND ENZYME INHIBITORS AND IN ASSAYS EMPLOYING ENZYME-LABELED SPECIFIC BINDING PAIRS LUMIGEN, INC. 2002-06-25 US disclosed
US-20010031869-A1 Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives LUMIGEN, INC. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031869-A1 Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives ALDH3A1, AADAC, SPR EGFR 2847/4885MAPT 4271/4885ALDH1A1 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.