Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15413502 | 0.80 | BACE1 (0.58) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL15413130 | 0.76 | EGFR (0.50) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL8947495 | 0.74 | EGFR (0.73) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL15413450 | 0.73 | ELANE (0.49) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL16912727 | 0.72 | EGFR (0.43) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL9878296 | 0.72 | ELANE (0.60) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL2077922 | 0.72 | KEAP1 (0.42) | ELANEMEN1KMT2AAPLNRALDH1A1 | |
| SCHEMBL8996320 | 0.71 | EGFR (0.45) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL16912731 | 0.71 | ERN1 (0.48) | ELANEEGFRPIM1MEN1KMT2A | |
| SCHEMBL8996346 | 0.71 | EGFR (0.56) | ELANEEGFRPIM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| EP-2872474-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | Georgia State University Research Foundation, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011753-A2 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | PCNA, KRAS, RECQL | ELANE 815/4885EGFR 2701/4885PIM1 3546/4885 |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | ELANE 815/4885EGFR 2701/4885PIM1 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.