Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996439 | 0.84 | TTR (0.57) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL8996347 | 0.82 | TTR (0.43) | ELANEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9572219 | 0.78 | EGFR (0.42) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL9572222 | 0.78 | EGFR (0.42) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL8996327 | 0.77 | ALDH1A1 (0.51) | ELANEMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8996330 | 0.76 | AMY1A (0.54) | KMT2AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9008524 | 0.75 | MAPT (0.46) | MEN1KMT2AALDH1A1CYP1A2MAPT | |
| SCHEMBL15413502 | 0.75 | BACE1 (0.58) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL8947495 | 0.74 | EGFR (0.73) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL3515014 | 0.73 | HTR7 (0.46) | ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |