Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385200 | 0.69 | ABCG2 (0.46) | GSK3BMAPKAPK2ABCG2POLBMAPT | |
| SCHEMBL4252678 | 0.67 | PDE3B (0.39) | CDK1GSK3AGSK3BCDK5NOTUM | |
| SCHEMBL18092278 | 0.66 | — | — | |
| SCHEMBL10871702 | 0.59 | PDE3B (0.36) | NPC1ALDH1A1POLB | |
| Water SCHEMBL28254092 | 0.59 | CA2 (0.69) | ALDH1A1 | |
| Water SCHEMBL28189314 | 0.59 | CA2 (0.69) | ALDH1A1 | |
| SCHEMBL45942 | 0.59 | CA2 (0.69) | ALDH1A1 | |
| SCHEMBL2503454 | 0.59 | CA2 (0.69) | ALDH1A1 | |
| SCHEMBL7591056 | 0.58 | PTGES (0.48) | XDH | |
| SCHEMBL1080585 | 0.57 | NOS3 (0.51) | UPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872492-A2 | PROCESS FOR RILPIVIRINE USING NOVEL INTERMEDIATE | Hetero Research Foundation (IN) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009968-A2 | PROCESS FOR RILPIVIRINE USING NOVEL INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2014-01-16 | — | — | WO | disclosed |