SCHEMBL8065707

SCHEMBL8065707

Cn1c(N)cc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
DAO P14920 1/20 0.50
MCL1 Q07820 1/20 0.50
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47
RECQL P46063 1/20 0.47
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
BRPF1 P55201 2/20 0.47
BRD4 O60885 1/20 0.47
KAT2B Q92831 1/20 0.47
BRD9 Q9H8M2 1/20 0.47
SLC9A1 P19634 1/20 0.46
TERT O14746 1/20 0.46
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617324 0.77 KMT2A (0.53) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL15417040 0.77 KMT2A (0.53) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL10103705 0.76 KMT2A (0.76) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL30349848 0.75 DAO (0.62) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL8538250 0.75 DAO (0.62) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL29378766 0.74 KMT2A (0.55) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL154592 0.74 KMT2A (0.55) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL8598225 0.74 NOS2 (0.43) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL10339713 0.74 KMT2A (0.50) KMT2ADAOMCL1ALDH1A1MAPT
SCHEMBL12182 0.74 RXFP1 (0.53) KMT2AALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254135-A Applying indole dye, developing with oxidizing system L'OREAL (FR) 1993-10-19 US claimed
CN-115141123-B Compound, preparation method thereof and application thereof in preparation of dual inhibitors of histone deacetylase and epoxide hydrolase 沈阳药科大学 2024-05-17 CN disclosed
EP-4272832-A2 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2023-11-08 EP disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20220396581-A1 COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS Janssen Biopharma, Inc. (US) 2022-12-15 US disclosed
US-20220396581-A1 COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS Janssen Biopharma, Inc. (US) 2022-12-15 US disclosed
CN-115141123-A Compound, preparation method thereof and application thereof in preparation of histone deacetylase and epoxide hydrolase dual inhibitor 沈阳药科大学 2022-10-04 CN disclosed
US-20210391545-A1 Metal Compounds, Methods, and Uses Thereof UNIV ARIZONA STATE (US) 2021-12-16 US disclosed
US-11114626-B2 Metal compounds, methods, and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-09-07 US disclosed
EP-2888240-A1 COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS Alios Biopharma, Inc. (US) 2015-07-01 EP disclosed
CN-104736530-A Compounds for the treatment of paramoxyvirus viral infections ALIOS BIOPHARMA INC 2015-06-24 CN disclosed
WO-2015042363-A1 MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-03-26 WO disclosed
WO-2014031784-A1 COMPOUNDS FOR THE TREATMENT OF PARAMOXYVIRUS VIRAL INFECTIONS ALIOS BIOPHARMA, INC. (US) 2014-02-27 WO disclosed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP disclosed
CN-1197860-C FAB I inhibitors SMITHKLINE BEECHAM CORP (CA) 2005-04-20 CN disclosed
CN-1378542-A Antigen binding fragment I inhibitors SMITHKLINE BEECHAM CORP (US) 2002-11-06 CN disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
EP-0550507-A1 INDOLE UREAS AS 5 HT RECEPTOR ANTAGONIST Beecham Group p.l.c. (GB) 1993-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396581-A1 COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS MAVS, SARS1, ZC3HAV1 KMT2A 3989/4885DAO 1333/4885MCL1 3951/4885
US-20210391545-A1 Metal Compounds, Methods, and Uses Thereof SOD1, SOD3, AOX1 KMT2A 3516/4885DAO 2039/4885MCL1 1493/4885
US-11716898-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND KMT2A 3480/4885DAO 3536/4885MCL1 2849/4885
US-11114626-B2 Metal compounds, methods, and uses thereof SOD1, SOD3, AOX1 KMT2A 3516/4885DAO 2039/4885MCL1 1493/4885
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH KMT2A 4874/4885DAO 226/4885MCL1 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.