Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266604 | 0.87 | ADORA3 (0.58) | F2RL3ADORA3CA12CA1CA2 | |
| SCHEMBL5395099 | 0.86 | HTR1B (0.50) | CNR2ADORA3CA12CA1CA2 | |
| SCHEMBL29952623 | 0.79 | F2RL3 (0.47) | F2RL3CNR2ADORA3CA12CA1 | |
| SCHEMBL7929572 | 0.79 | F2RL3 (0.47) | F2RL3CNR2ADORA3CA12CA1 | |
| SCHEMBL29902834 | 0.78 | LMNA (0.68) | F2RL3CNR2ADORA3CA9ADORA2A | |
| SCHEMBL10649682 | 0.78 | LMNA (0.68) | F2RL3CNR2ADORA3CA9ADORA2A | |
| SCHEMBL73415 | 0.78 | LMNA (0.58) | ADORA3CA12CA1CA2CA9 | |
| SCHEMBL7929575 | 0.77 | CNR2 (0.44) | F2RL3CNR2ADORA3CA12CA1 | |
| SCHEMBL8196245 | 0.76 | ALDH1A1 (0.42) | ADORA3CA12CA1CA2CA9 | |
| SCHEMBL11347672 | 0.76 | CNR2 (0.48) | F2RL3CNR2ADORA3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623407-B2 | Gabapentin-containing solid compositions and process for preparing the same | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |