Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73415 | 0.83 | LMNA (0.58) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL266604 | 0.79 | ADORA3 (0.58) | ALDH1A1SMN1; SMN2HSD17B10LMNAKMT2A | |
| SCHEMBL26756506 | 0.77 | F2RL3 (0.42) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL9961609 | 0.76 | LMNA (0.41) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL15417664 | 0.76 | F2RL3 (0.47) | ALDH1A1KDM4EHPGDLMNACA12 | |
| SCHEMBL5395099 | 0.75 | HTR1B (0.50) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL4428324 | 0.74 | MAOB (0.58) | ALDH1A1MAOACYP2A6ADORA3ADORA2A | |
| SCHEMBL31033310 | 0.73 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL5003621 | 0.72 | MAOA (0.59) | KDM4EMAOACA12CA1CA2 | |
| SCHEMBL27462719 | 0.72 | ADORA2A (0.44) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081282-A2 | PROCESS FOR THE SYNTHESIS OF N9-(3,5-DICHLORO-4-PYRIDYL)-6- DIFLUOROMETHOXYBENZO(4,5)FURO(3,2-C)PYRIDINE-9-CARBOXAMIDE AND SALTS THEREOF | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-07-10 | — | — | WO | disclosed |