Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871999 | 0.83 | SLC6A2 (0.77) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL871962 | 0.75 | SLC6A2 (0.81) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10007822 | 0.74 | SLC6A4 (0.80) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL872344 | 0.74 | SLC6A2 (0.81) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3521787 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL15422684 | 0.73 | SLC6A3 (0.85) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15422503 | 0.73 | SLC6A3 (0.85) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL872240 | 0.72 | SLC6A4 (0.85) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2272723 | 0.72 | SLC6A4 (0.81) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL873021 | 0.71 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296681-B2 | Cycloalkylmethylamines | REVIVA PHARMACEUTICALS, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-9096515-B2 | Methods of using cycloalkylmethylamine derivatives | REVIVA PHARMACEUTICALS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140066500-A1 | CYCLOALKYLMETHYLAMINES | REVIVA PHARMACEUTICALS, INC. (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140024709-A1 | METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066500-A1 | CYCLOALKYLMETHYLAMINES | PNMT, TPH1, TPH2 | SLC6A4 15/4885SLC6A3 60/4885SLC6A2 77/4885 |
| US-20140024709-A1 | METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | PNMT, TPH1, TPH2 | SLC6A4 20/4885SLC6A3 66/4885SLC6A2 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.