Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.67 |
| ▸ | SI | P14410 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1094062 | 0.95 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5749896 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3196220 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1068041 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| Lithium Ion SCHEMBL3201231 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3183138 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29455991 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| Lithium Ion SCHEMBL15950284 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13278768 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 | |
| Zinc Ion SCHEMBL13278766 | 0.95 | GAA (0.67) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119980520-A | Preparation method of aluminum polycarboxylate precursor and aluminum oxide fiber | 齐鲁工业大学(山东省科学院) | 2025-05-13 | — | — | CN | claimed |
| CN-119661437-A | Synthesis method of 4-acetamido-1H-pyrazole | 上海毕得医药科技股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119409630-A | Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2025-02-11 | — | — | CN | claimed |
| CN-119118927-A | Synthesis method of 3-chloro-6-methylpyridazine | 上海毕得医药科技股份有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-118955316-A | Preparation method of roflumilast intermediate | 石家庄龙泽制药股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118666744-B | Synthesis method of nemonoxacin key intermediate | 成都天兴致远生物科技有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-117069692-B | 5-Hydroxypyrazole derivative, half-sandwich ruthenium complex, and preparation methods and applications thereof | 广西中医药大学 | 2024-08-27 | — | — | CN | claimed |
| CN-115938640-B | Acetic acid-resistant solar cell silver paste and preparation method thereof | 江西佳银科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20230416252-A1 | PROCESS TOWARD THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE | JANSSEN PHARMACEUTICA NV (BE) | 2023-12-28 | — | — | US | claimed |
| CN-117126184-A | Supermolecule photosensitizer and preparation method and application thereof | 北京师范大学 | 2023-11-28 | — | — | CN | claimed |
| EP-0837062-B1 | Preparation of cyclocarbonates | HOFFMANN LA ROCHE (CH) | 2003-12-03 | — | — | EP | claimed |
| US-6580004-B1 | Process for preparing potassium monoethyl malonate | DEGUSSA AG (DE) | 2003-06-17 | — | — | US | claimed |
| EP-0950653-B1 | Process for the preparation of potassium monoethylmalonate | DEGUSSA (DE) | 2001-11-21 | — | — | EP | claimed |
| EP-1091927-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PROPENOIC ACID ESTERS | Vyas, Sharad Kumar (IN) | 2001-04-18 | — | — | EP | claimed |
| US-6172257-B1 | Process for preparing potassium monoethyl malonate | CREANOVA SPEZIALCHEMIE GMBH (DE) | 2001-01-09 | — | — | US | claimed |
| WO-2000000460-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED PROPENOIC ACID ESTERS | VYAS SHARAD KUMAR (IN) | 2000-01-06 | — | — | WO | claimed |
| US-5817838-A | CATALYTIC CYCLIZATION OF A CORRESPONDING ACETYLENIC ALCOHOL USING QUATERNARY AMMONIUM OR PHOSPHONIUM SALT MIXTURE WITH SILVER SALT | ROCHE VITAMINS INC. (US) | 1998-10-06 | — | — | US | claimed |
| EP-0652213-B1 | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS CO LTD (JP) | 1997-08-27 | — | — | EP | claimed |
| US-5508446-A | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | claimed |
| EP-0652213-A1 | Method for producing alkyl 3-phthalidylideneacetate | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1995-05-10 | — | — | EP | claimed |