Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 13/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR1E | P28566 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469329 | 0.82 | HTR2B (0.58) | HTR2BHTR2CHTR1DHTR2AHTR1E | |
| SCHEMBL3305343 | 0.73 | HTR2B (0.51) | HTR2BHTR2CHTR1DHTR2AHTR1E | |
| SCHEMBL3372129 | 0.69 | HTR2B (0.46) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL26117247 | 0.68 | HTR2B (0.76) | HTR2BHTR2CHTR1DHTR3AHTR7 | |
| SCHEMBL1534272 | 0.68 | HTR2B (0.76) | HTR2BHTR2CHTR1DHTR3AHTR7 | |
| SCHEMBL1686982 | 0.68 | HTR2B (0.76) | HTR2BHTR2CHTR1DHTR3AHTR7 | |
| SCHEMBL30608416 | 0.68 | HTR2B (0.76) | HTR2BHTR2CHTR1DHTR3AHTR7 | |
| SCHEMBL11050644 | 0.67 | HTR2B (0.74) | HTR2BHTR2CHTR1DHTR3AHTR7 | |
| SCHEMBL3329469 | 0.66 | HTR2B (0.43) | HTR2BHTR2CHTR1DHTR2AHTR3A | |
| SCHEMBL15423051 | 0.65 | HTR2B (0.43) | HTR2BHTR2CHTR1DHTR2AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751847-B2 | Methods and compositions related to neuroactive thiazoline compounds | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-05 | — | — | US | disclosed |
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018400-A1 | METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS | TACR2, TACR3, TACR1 | HTR2B 58/4885HTR2C 9/4885HTR1D 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.