SCHEMBL15424231

SCHEMBL15424231

CC(=O)Nc1ccc(/N=N/c2ccc3cc(NC(=O)Nc4ccc5c(O)c(/N=N/c6ccccc6)c(S(=O)(=O)O)cc5c4)ccc3c2O)cc1

nearest known ligand 0.89

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 1/20 0.89
▸ EP300 Q09472 1/20 0.89
▸ PRMT6 Q96LA8 1/20 0.89
▸ PRMT1 Q99873 1/20 0.89
▸ ENPP2 Q13822 12/20 0.71
▸ CD40 P25942 1/20 0.67
▸ CD40LG P29965 1/20 0.67
▸ CA2 P00918 1/20 0.51
▸ CA3 P07451 1/20 0.51
▸ NPC1 O15118 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ PHLPP2 Q6ZVD8 1/20 0.46
▸ MPL P40238 1/20 0.44
▸ CTRC Q99895 1/20 0.44
▸ CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637780 0.94 PRMT1 (1.00) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL23259402 0.94 PRMT1 (1.00) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL30371624 0.94 PRMT1 (0.98) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL10623011 0.94 PRMT1 (0.98) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL10623083 0.94 PRMT1 (0.98) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL29538633 0.88 ENPP2 (0.86) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL10622996 0.86 PRMT1 (0.84) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13046146 0.84 PRMT1 (0.79) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL20621514 0.84 PRMT1 (0.80) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL29926756 0.83 ENPP2 (0.79) PRMT3EP300PRMT6PRMT1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 — — US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 — — US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 — — US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PRMT3 1928/4885EP300 621/4885PRMT6 2697/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PRMT3 1928/4885EP300 621/4885PRMT6 2697/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PRMT3 1928/4885EP300 621/4885PRMT6 2697/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 PRMT3 1928/4885EP300 621/4885PRMT6 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback