SCHEMBL23259402

SCHEMBL23259402

CC(=O)Nc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(NC(=O)Nc4ccc5c(O)c(N=Nc6ccccc6)c(S(=O)(=O)O)cc5c4)ccc3c2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 3/20 1.00
▸ PRMT3 O60678 1/20 1.00
▸ EP300 Q09472 1/20 1.00
▸ PRMT6 Q96LA8 1/20 1.00
▸ ENPP2 Q13822 10/20 0.76
▸ CD40 P25942 1/20 0.66
▸ CD40LG P29965 1/20 0.66
▸ CA2 P00918 1/20 0.56
▸ CA3 P07451 1/20 0.56
▸ NPC1 O15118 2/20 0.52
▸ MAPT P10636 2/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ PHLPP2 Q6ZVD8 2/20 0.50
▸ LMNA P02545 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ CARM1 Q86X55 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637780 1.00 PRMT1 (1.00) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL30371624 0.99 PRMT1 (0.98) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL10623083 0.99 PRMT1 (0.98) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL10623011 0.99 PRMT1 (0.98) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL15424231 0.94 PRMT3 (0.89) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL29538633 0.93 ENPP2 (0.86) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL10622996 0.91 PRMT1 (0.84) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL13046146 0.89 PRMT1 (0.79) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL20621514 0.89 PRMT1 (0.80) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL29926756 0.88 ENPP2 (0.79) PRMT1PRMT3EP300PRMT6ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210115489-A1 NOVEL MEDIATOR KIKKOMAN CORPORATION (JP) 2021-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115489-A1 NOVEL MEDIATOR MPO, EPX, LPO PRMT1 2067/4885PRMT3 2672/4885EP300 623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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